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Monsturd (2003)

IMDb: 3.6
2003

A serial killer mutates with a chemical inside a sewer, to become a monster made of human waste just as the FBI and police are onto him

Retardead (2008)

IMDb: 3.1
2008

The evil Dr Stern returns, armed with a lethal intelligence serum that yields horrific results at the Butte County Institute for Special Education